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Definitions (17)
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progenitor cells
Partially commited cells found in all tissues that are still able to proliferate, and have not yet commited to terminal differentiation down one (unipotent) or more (multipotent) lineages.
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stem cell niche
The location within a tissue where adult stem cells reside. It is characterized by a very specific environment, which controls both the maintenance of the stem cell pool, as well as the release of cel [..]
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adult stem cells
Unspecialized, multipotent cells with a high differentiation potential found in virtually all tissues of the body. Their capacity for asymmetrical division allows them to both maintain the pool of ste [..]
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keratinocyte
An epithelial cell that produces keratins. Most commonly located in the epidermis, although also present in other epithelia (e.g. cornea, oral mucosa).
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embryonic stem cells
Pluripotent cells, able to differentiate into all tissue types of the body. Mainly isolated from the inner cell mass of the blastocyst that forms during early embryonic development.
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epithelium
Tissue composed of one or more cell layers which form the covering of internal and external surfaces of the body and its organs. Epithelial layers are separated from the underlying connective tissue b [..]
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epidermis
Multilayered epithelium forming the uppermost layer of the skin. Comprised primarily of keratinocytes. Key role is to provide the barrier function essential for protecting the body. The barrier is for [..]
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confluency
The amount of surface area of the tissue culture plate that is covered with cells expressed as a percent (e.g. 100% means that the whole culture vessel surface is covered with cells).
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dermis
Layer of the skin, located below the epidermis. Comprised primarily of fibroblasts in an extracellular matrix which consists mainly of collagen. Also contains nerve endings, sweat and sebaceous glands [..]
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primary cell culture
Term used by researchers denoting a recently isolated cell culture. Strictly speaking, only cells immediately following isolation (e.g. up to passage 1) are primary cells, but the term is commonly use [..]
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