Any molecule that improves the activity of a different molecule; e.g., a hormone, which acts as an agonist when it binds to its receptor, thus triggering a biochemical response.

A group of 20 different kinds of small molecules that link together in long chains to form proteins. Often referred to as the "building blocks" of proteins. The sequence of amino acids in a [..]

A drug whose structure is related to that of another drug but whose chemical and biological properties may be quite different.

A molecule that blocks the ability of a given chemical to bind to its receptor, preventing a biological response.

Trademark of Argonaut Technologies, San Carlos, California, USA. Beaded solid support with a crosslinked polystyrene core and grafted linear poly (ethylene glycol) (PEG) chains with terminal functiona [..]

Form of parallel synthesis in which the reaction vessels are maintained in a specified spatial distribution, e.g. the wells of a 96-well plate or pins held in a rack.

A biological test, measurement or analysis to determine whether compounds have the desired effect either in a living organism, outside an organism, or in an artificial environment.

An aliquot of a library which will allow the library to be screened in a single assay. Particularly applicable to libraries prepared by split/pool procedure, where it pertains to the number of particl [..]

Determination of the relative strength of a drug by comparing its effect on a test organism with that of a standard preparation.

Compounds that are either naturally occurring or identical to naturally occurring substances. Examples include hormones, pheromones, and enzymes.