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Definitions (264)
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substrain
An inbred strain that was separated from an inbred ancestor before F40, or separated by greater than 100 generations from a common inbred ancestor, or possesses a known genetic characteristic (mutat [..]
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antimorph
A mutant allele that antagonizes the function of another gene and acts in a semi-dominant manner.
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chiasma
The cross-shaped exchange configuration between non sister chromatids of homologous chromosomes that is visible during prophase I of meiosis.
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cistron
A nucleotide sequence coding for a single polypeptide.
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heterosis
The superiority of hybrids over either inbred parent; a.k.a. hybrid vigor.
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methylation
Biochemical process involving addition of methyl groups to DNA, silencing a gene or cluster of genes.
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aaalac international
Association for Assessment and Accreditation of Laboratory Animal Care International. A voluntary accreditation program for laboratory animal facilities and programs.
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aalas
American Association for Laboratory Animal Science.
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acetylation
Biochemical process involving addition of acetyl groups to DNA, favoring gene expression.
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acrocentric chromosome
Chromosome pattern in which the centromere is assymetrically toward one end and the telomeres are at the ends (in contrast to telocentric and metacentric). Mice do not have acrocentric chromosomes.
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