The area of the body between the anus and the base of the scrotum. In brachytherapy, needles containing radioactive seeds or in HDR, thin tubes are implanted in the prostate through the perineum.

Assisting or aiding. Used to describe additional treatments administered in addition to a definitive therapy. For EBRT this usually refers to androgen deprivation given after ERBT is finished.

A hormone with masculinizing properties, for example, testosterone. Androgens stimulate growth of both normal prostate and most malignant prostatic cells.

A therapeutic strategy designed to decrease circulating levels of the male androgen testosterone, and its related compounds. Can be done by removing organs that produce testosterone (for example, test [..]

Oral agents flutamide (Eulexin), nilutamide (Nilandron) and bicalutamide (Casodex), that block the action of testosterone and its active metabolite dihydrotestosterone (DHT) at the cellular level by i [..]

A clinical syndrome in which discontinuation of an anti-androgen in a patient may result in a decline in PSA, symptomatic improvement or tumor regression; effective in 15 to 30 percent of patients for [..]

A device used to deliver or hold a radioactive source during brachytherapy.

Non-cancerous enlargement of the prostate gland, which often results in difficulty with urination. The incidence increases with age.

Sampling of tissue.

Pieces of metal alloy that can be used to shape the EBRT beam.