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Definitions (147)
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cold chain
A system used to transport vaccines at a constant temperature involving a chain of refrigerators and portable cool boxes. Most vaccines and diluents need to be transported and stored in a cold chain b [..]
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monovalent vaccine
A monovalent vaccine is designed to immunize against a single antigen or single microorganism whereas polyvalent vaccines aim to immunize against several strains of the same microorganism, or against [..]
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a
Acellular pertussis vaccine
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adjuvant
A pharmacological agent (e.g., aluminum salt, oil-in-water emulsions) that modifies the effect of other agents, such as a drug or vaccine, while having few if any direct effects when given by itself. [..]
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adrenaline
A drug used to treat severe allergic reaction (anaphylaxis). Also a hormone produced by the adrenal gland. Adverse drug reaction
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adverse event
Any untoward medical occurrence that may appear during treatment with a pharmaceutical product but which does not necessarily have a causal relationship with the treatment. Adverse event following imm [..]
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adverse event of special interest
A relatively new AEFI classification that started with pandemic vaccine development. AESI refers to adverse events of significant scientific, medical, and public interest among pandemic vaccines. AEFI [..]
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anaphylaxis
An acute, multi-system, allergic reaction (IgE mediated) to a substance, such as vaccination, drugs, and food. Symptoms of anaphylaxis may include breathing difficulties, loss of consciousness, and a [..]
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antibody
A special protein produced by plasmocytes in response to antigens (foreign substances, e.g., bacteria or viruses). Antibodies bind with antigens on microorganisms as one of the initial steps of the bo [..]
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asthma
Chronic respiratory disease characterized by constriction of the bronchial tubes to the lungs, which causes sudden and recurring breathing problems, coughing, chest tightness and wheezing. Asymptomati [..]
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