For proteins, a process in which a protein unravels and loses its native conformation, thereby becoming biologically inactive. For DNA, the separation of the two strands of the double helix. Denaturat [..]

1845, earlier in French and German; see denature + -ation.

Process that separates the strands of doublestranded DNA when DNA is heated. © 2005 by W. H. Freeman and Company. All rights reserved. Pierce, B. Genetics: A conceptual approach. 2nd Edition.

With refer to nucleic acids, it refers to the conversion from double-stranded to the single-stranded state, often achieved by heating or alkaline conditions. This is also called "melting& [..]

Rendering inactive by permanently disrupting the 3D structure of an enzyme, for example by boiling or extremes of pH.

The disruption of the native folded structure of a nucleic acid or protein molecule; may be due to heat, chemical treatment, or change in pH.

(French : dénaturation) Formation of a single DNA strand from a double strain under heating of chemical bonds responsible for base pairing.

Changes the native structure of a protein by either heats or acid.

Denaturation is the loss of the native configuration of the macromolecule, such as the unfolding of the tertiary structure of an antibody protein. Denaturation usually results in the loss of the macromolecule's biological or immunological reactivity or solubility.

The irreversible process in which the structure of a protein is disrupted, resulting in a partial or complete loss of function. This can be caused by a number of things, the most common of which are h [..]

Drastic alteration in the conformation of a protein or nucleic acid due to disruption of various noncovalent bonds caused by heating or exposure to certain chemicals; usually results in loss of biolog [..]

Disruption of the secondary structure of Nucleic Acids by Heat, Extreme pH or chemical treatment. Double strand DNA is "melted" by dissociation of the non-covalent Hydrogen bonds and hydroph [..]

Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.

Denaturation is a process in which proteins lose their structure (terciary and secondary) by contact with and external force, stress, or compound such as High Heat, a strong base or acid, concentrated [..]

Is the breakdown or disruption of cell structures. If proteins in a living cell are denatured it results in a disrupton of cell activity and possibly cell death. Denatured proteins exhibit a wide rang [..]

1)The separation of the two strands of a DNA double helix, or 2) the severe disruption of the hydrogen bonded structure of any complex molecule without breaking the covalent bonds of its chains.

1. The separation of the two strands of a double-stranded nucleic acid caused by treatments that overcome hydrogen bonding, e.g., heat. 2. A usually irreversible change in the conformation of a protein caused by treatments that overcome hydrogen bonding, hydrophobic interactions, or other chemical forces that maintain the structure of proteins, e.g [..]