A member of a group of enzymes that can break down proteins, such as collagen, that are normally found in the spaces between cells in tissues (i.e., extracellular matrix proteins). Because these enzym [..]

a proteolytic enzyme that degrades extracellular matrix proteins, such as collagen and elastin.

Matrix Metalloproteinases that are associated with the Cell Membrane, either through transMembrane domains or Glycosylphosphatidylinositol ANCHORS. Membrane-type Matrix Metalloproteinases may act with [..]

A transmembrane domain-containing matrix metalloproteinase that plays a Role in the cleavage of Proteins in the pericellular Environment. It is synthesized as an inactive zymogen that is activated by [..]

A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of Proprotein Convertases. Matrix metalloproteinase 16 [..]

A secreted matrix metalloproteinase that is believed to play a Role in Extracellular Matrix remodeling and Cell fate determination during normal and Pathological Processes. Matrix metalloproteinase 11 [..]

An enzyme whose activation levels are imaged with PET to help assess changes in the size, shape, and function of the heart after injury such as a heart attack to (called ventricular remodeling).

A member of a group of enzymes that can break down proteins, such as collagen, that are normally found in the spaces between cells in tissues (i.e., extracellular matrix proteins). Because these enzymes need zinc or calcium atoms to work properly, they are called metalloproteinases. Matrix metalloproteinases are involved in wound healing, angiogene [..]