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proto-oncogeneA normal gene which, when altered by mutation, becomes an oncogene that can contribute to cancer. Proto-oncogenes may have many different functions in the cell. Some proto-oncogenes provide signals that lead to cell division. Other proto-oncogenes regulate programmed cell death (apoptosis). The defective versions of proto-oncogenes, known as oncoge [..]
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proto-oncogeneA gene involved in normal cell growth. Mutations (changes) in a proto-oncogene may cause it to become an oncogene, which can cause the growth of cancer cells.
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proto-oncogene(pro-toh-onk-oh-jeen) A normal cellular gene corresponding to an oncogene; a gene with a potential to cause cancer, but that requires some alteration to become an oncogene.
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proto-oncogeneNormal cellular gene that controls cell division. When mutated, it may become an oncogene and contribute to cancer progression. © 2005 by W. H. Freeman and Company. All rights reserved. Pierce [..]
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proto-oncogeneA gene present in a normal cell which carries out a normal cellular function, but which can become an oncogene under certain circumstances. The prefix "c-" indicates a cellular gene, [..]
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proto-oncogeneSee oncogene. protochordates
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proto-oncogeneA gene present in a normal cell which carries out a normal cellular function, but which can become an oncogene under certain circumstances. The prefix "c-" indicates a cellular gene, and is generally used for proto-oncogenes (examples: c-myb
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proto-oncogeneA cellular gene that can undergo modification to a cancer-causing gene (oncogene).
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proto-oncogene A eukaryotic gene that functions to promote cellular proliferation or inhibit apoptosis, in which gain-of-function mutations (oncogenes) are associated with cancer.
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proto-oncogeneA normal gene that has the potential to become an oncogene.
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proto-oncogene(n) a normal gene that has the potential to become an oncogene
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proto-oncogeneA normal cellular gene that encodes a protein usually involved in regulation of cell growth or proliferation and that can be mutated into a cancer-promoting oncogene, either by changing the protein-co [..]
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proto-oncogeneA gene involved in normal cell growth. Mutations (changes) in a proto-oncogene may cause it to become an oncogene, which can cause the growth of cancer cells.
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proto-oncogeneNormal cellular gene, usually involved in growth control, from which an oncogene is derived as the result of a somatic mutation or viral recombination.
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proto-oncogeneAKA: Cellular oncogene The non-activated form of a cellular oncogene in an untransformed cell. A gene that, when mutated or otherwise affected, becomes an oncogene.
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proto-oncogeneOncogenes are altered forms of normal cellular genes called proto-oncogene. Many proto-oncogenes are homologous to viral oncogenes and involved in the control of cell proliferation or differentiation. Mutations, amplifications or rearrangements of proto-oncogenes lead to upregulated or deregulated cell growth and allow them to function as oncogenes [..]
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