The platelets interfere with the body's normal clotting mechanism can't work and there is abnormal bleeding.

One member of a pair or series of genes that occupy a specific position on a specific chromosome. MPN community discusses "allele burden" as a metric that may or may not be related t [..]

t A procedure in which a person receives blood-forming stem cells (cells from which all blood cells develop) from a genetically similar, but not identical, donor. This is often a sister or brother, bu [..]

When the number of red blood cells is below normal, it can result in fatigue, weakness, and shortness of breath.

The process of programmed cell death (PCD) that may occur in multicellular organisms.

 Enzymes essential to cell proliferation. The enzyme helps the dividing cell dispense its genetic materials to its daughter cells

 Substance which blocks enzymes (Aurora kinases) involved in cell division and may kill cancer cells.

 A transplant in which a patient's own blood-forming stem cells are collected. He or she is then treated with high doses of chemotherapy, or a combination of chemotherapy and radiation. The hi [..]

Undeveloped, immature blood cells in the bone marrow that develop into mature blood cells

A procedure used to remove soft tissue, called marrow, from inside the bone. A reading of a Bone Marrow Biopsy to detect the amount of fibrosis in the bone marrow is often used in part to diagnose mye [..]