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Definitions (271)
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void space
The space within a desolvated crystal that is not occupied by atoms.
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birefringence
An optical property of all anisotropic crystals (i.e., virtually all drugs) observed as light and dark areas while the sample is rotated on the microscope stage of a polarizing microscope.
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activation energy
A physicochemical quantity that represents the barrier for a chemical reaction.
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adjunct
A substance added to a drug formulation to improve its pharmaceutical performance.
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amorphous form
A solid that does not give a distinctive powder X-ray diffraction pattern. Amorphous solids are usually considered noncrystalline materials (i.e., glasses).
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angle of incidence
The angle at which X-rays strike a plane in the crystal.
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anhydrate
A crystal form that contains no solvent of crystallization.
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anisotropic behavior
A term used to describe cases where a solid-state reaction proceeds through different directions of the crystal at different rates; also referring to any observed property that varies in different directions in or on a crystal.
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atomic displacement parameter
A measure of the mobility or disorder of a given atom in a crystal structure, formerly called the temperature factor.
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