A rare genetic (inherited) disorder characterized by the breakdown or loss of the myelin sheath surrounding nerve cells in the brain and progressive dysfunction of the adrenal gland. Adrenoleukodystrophy (ALD) is one of a group of genetic disorders called the leukodystrophies that cause damage to the myelin sheath of the nerve fibers in the brain. [..]

noun. A hereditary disorder or illness that is marked by the decomposition of the myelin sheath which encompasses the brain's nerves as well as the ongoing decomposition of the adrenal gland. Whe [..]

An X-linked genetic disease characterised by the progressive deterioration of brain signalling and function.

An X-linked recessive disorder characterized by the accumulation of saturated very long chain Fatty Acids in the Lysosomes of Adrenal Cortex and the White matter of Central Nervous System. This Diseas [..]

An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This diseas [..]

<radiology> X-linked recessive, demyelination of cerebral white matter, adrenal insufficiency (unresponsive to ACTH), CT: white-matter disease: occipital regions to frontal, progression to generalised atrophy, NM: increased uptake in involved regions, ** dysmyelinating disease, white-matter disease Abbreviation: ALD (12 Dec 1998)