Proteins involved in the process of transcription – often activating this process.

Transcription factors are proteins involved in the process of converting, or transcribing, DNA into RNA. Transcription factors include a wide number of proteins, excluding RNA polymerase, that initiat [..]

Endogenous substances, usually Proteins, which are effective in the initiation, stimulation, or termination of the Genetic Transcription process.

Basic helix-loop-helix (bHLH) domain-containing Proteins that play important Roles in Circadian Rhythm Regulation. They combine with CLOCK Proteins to form heterodimeric Transcription Factors that are [..]

Activating Transcription Factors were originally identified as DNA-Binding Proteins that interact with early promoters from Adenoviruses. They are a Family of Basic Leucine Zipper Transcription Factor [..]

A Family of DNA-binding Transcription Factors that contain a basic Helix-Loop-Helix Motif.

A Family of Transcription Factors that contain regions rich in basic residues, Leucine Zipper domains, and Helix-Loop-Helix Motifs.

A large superfamily of Transcription Factors that contain a region rich in Basic Amino Acid residues followed by a Leucine Zipper domain.

A sub-Family of Steroid Receptor-related Orphan Nuclear Receptors that have specificity for a variety of DNA sequences related to AGGTCA. COUP Transcription Factors can heterodimerize with a variety o [..]

A Family of Basic Helix-Loop-Helix Transcription Factors that control expression of a variety of Genes involved in Cell Cycle Regulation. E2F Transcription Factors typically form heterodimeric complex [..]

A Family of Transcription Factors that are induced by Growth FACTORS and contain a highly conserved DNA-binding domain composed of three Zinc Finger Motifs.

A Family of Transcription Factors that share a unique DNA-binding domain. The name derives from viral Oncogene-derived protein Oncogene Protein v-ets of the Avian Erythroblastosis Virus.

A subclass of winged helix DNA-Binding Proteins that share homology with their founding member fork head protein, Drosophila.

A Family of Transcription Factors that contain two Zinc Finger Motifs and bind to the DNA sequence (A/T)GATA(A/G).

A Family of Transcription Factors found primarily in Plants that bind to the G-box DNA sequence CACGTG or to a Consensus Sequence CANNTG.

Transcription Factors that form transcription initiation complexes on DNA, bind to specific DNA-Directed RNA Polymerases and are required to initiate transcription. Although their binding may be local [..]

A Family of Transcription Factors that share an N-terminal Helix-Turn-Helix Motif and bind Interferon-inducible promoters to control Gene Expression. IRF Proteins bind specific DNA sequences such as I [..]

A Family of Zinc Finger Transcription Factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their Zinc Finger Motifs [..]

Maf Transcription Factors are a Family of Basic-Leucine Zipper Transcription Factors that are closely related to v-maf Oncogene Protein. The c-maf Proto-Oncogene Protein was the first mammalian Maf Tr [..]

A large maf protein that regulates Hindbrain development, contributes to Cell Differentiation of Monocytes, and interacts with Ets-1 Transcription Factor.

A Family of Transcription Factors characterized by the presence of highly conserved Calcineurin- and DNA-binding domains. NFAT Proteins are activated in the Cytoplasm by the Calcium-dependent phosphat [..]

Transcription Factors that were originally identified as site-specific DNA-Binding Proteins essential for DNA Replication by Adenoviruses. They play important Roles in Mammary Gland function and devel [..]

A Family of POU Domain Factors that bind the octamer motif ATTTGCAT in enhancer and Promoter Regions to regulate Gene Expression.

A Family of Transcription Factors that contain a single cut domain and a divergent homeodomain. They regulate Gene Networks by controlling the expression of other Transcription Factors and they play a [..]

A Family of Vertebrate Homeodomain Proteins that share homology with orthodenticle protein, Drosophila. They regulate Genetic Transcription and play an important Role in Embryonic Development of the B [..]

A Family of Histone Acetyltransferases that is structurally-related to CREB-Binding Protein and to E1A-Associated p300 Protein. They function as transcriptional coactivators by bridging between DNA-bi [..]

A Family of Transcription Factors that control Embryonic Development within a variety of Cell Lineages. They are characterized by a highly conserved paired DNA-binding domain that was first identified [..]

A Family of Transcription Factors that bind to the cofactor Core Binding Factor beta Subunit to form Core Binding Factor. Family members contain a highly conserved DNA-binding domain known as the runt [..]

A large Family of structurally-related Transcription Factors that were originally discovered based upon their close Sequence Homology to an HMG-Box Domain found in Sex-Determining Region Y Protein. Ma [..]

A subclass of SOX Transcription Factors that are expressed in neuronal Tissue where they may play a Role in the Regulation of Cell Differentiation. Members of this subclass are generally considered to [..]

A subclass of SOX Transcription Factors that are expressed in neuronal Tissue where they may play a Role in the Regulation of Cell Differentiation. Members of this subclass are generally considered to [..]

A subclass of closely-related SOX Transcription Factors. Members of the group have been found expressed in developing neuronal Tissue, Lymphocytes, and during Embryonic Development.

A subclass of closely-related SOX Transcription Factors. In addition to a conserved HMG-Box Domain, members of this group contain a Leucine Zipper motif which mediates protein Dimerization.

A subclass of closely-related SOX Transcription Factors. Members of this subfamily have been implicated in regulating the differentiation of Oligodendrocytes during Neural Crest formation and in Chond [..]

A subclass of closely-related SOX Transcription Factors. Members of this subclass are expressed in VASCULAR Endothelial Cells and may play a Role in vasculogenesis.

A Family of DNA-Binding Proteins that contain three Zinc Fingers at their carboxy termini. They are Transcription Factors that have specificity for GC boxes.

A Family of Transcription Factors containing SH2 DOMAINS that are involved in CYTOKINE-mediated Signal Transduction. STAT Transcription Factors are recruited to the cytoplasmic region of Cell Surface [..]

A Family of DNA-Binding Proteins that are primarily expressed in T-Lymphocytes. They interact with beta Catenin and serve as transcriptional activators and repressors in a variety of developmental pro [..]

Factors that form a preinitiation complex at promoters that are specifically transcribed by RNA Polymerase I.

The so-called General Transcription Factors that bind to RNA Polymerase II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In [..]

Factors that bind to RNA Polymerase III and aid in transcription. They include the assembly factors TFIIIA and TFIIIC and the Initiation Factor TFIIIB. All combine to form a preinitiation complex at t [..]

A subfamily of HELIX-TURN-HELIX DNA-Binding Proteins that contain a variable length loop adjacent to the HTH Motif. The loop connects two anti-parallel strands and Forms a wing when bound to DNA.

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.

Transcription factors that form transcription initiation complexes on DNA, bind to specific DNA-DIRECTED RNA POLYMERASES and are required to initiate transcription. Although their binding may be local [..]

The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In [..]

Factors that bind to RNA POLYMERASE III and aid in transcription. They include the assembly factors TFIIIA and TFIIIC and the initiation factor TFIIIB. All combine to form a preinitiation complex at t [..]

Specific proteins that are required for the initiation of transcription by each of the three eukaryotic RNA

Proteins in eukaryotes that regulate the transcription of other genes by binding to regulatory sequences of the gene, interaction with one another and with the RNA polymerase.