memory cells are a subset of T cells and B cells that have been exposed to specific antigens and can then proliferate (recognize the antigen and divide) more readily when the immune system re-encounte [..]

a virus-like particle that resembles a virus but does not contain its genetic information and cannot replicate. In some viral diseases pseudovirions can interfere with infection by the real infectious [..]

Initiative Menu About Us About UsCareersBenefitsCompensationStrategic PlanOur HistorySeth Berkley, FounderSupplier Diversity What We Do ScienceHIV Vacci [..]

a substance sometimes included in a vaccine formulation to enhance or modify the immune-stimulating properties of a vaccine.

in a clinical trial, an unwanted effect detected in participants and attributed to the study vaccine.

a genetically engineered HIV vaccine composed of a live, weakened canarypox virus (ALVAC™) into which parts of genes for non-infectious components of HIV have been inserted. When ALVAC™ infects a huma [..]

the heightened immunologic reaction elicited by a second or subsequent exposure to a particular pathogenic microorganism (e.g., bacterium, fungus, virus), toxin, or antigen. (See also memory cells.)

an infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (e.g., bacteria, viruses) or toxins. Antibodies, known generally [..]

any substance that stimulates the immune system to produce antibodies. Antigens are often foreign substances such as invading bacteria or viruses. (See also immunogen.)

an antibody that recognizes and binds to the antigen-binding site of another antibody. In HIV vaccines, anti-idiotype vaccines are made from antibodies generated against antibodies to the virus.