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Definitions (76)

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acetylcholinesterase inhibitors


A class of drugs used to treat mild to moderate dementia in Parkinson's disease. These drugs increase brain levels of a neurotransmitter called acetylcholine, which helps neurons communicate with [..]
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with certain limitations -
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aggregate


A clumping of proteins inside cell bodies in the brain, which may be toxic. Aggregation of the protein alpha-synuclein is found in Lewy bodies, a pathological hallmark of Parkinson's disease. See [..]
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alpha-synuclein


A protein normally found in neurons, and present in high concentrations in Lewy bodies. A genetic mutation in this protein is the basis for a rare inherited form of Parkinson's disease. For more [..]
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anticholinergic


A class of drugs often effective in reducing the tremor of Parkinson's disease. They work by blocking the action of acetylcholine, a neurotransmitter in the brain. However, because acetylcholine [..]
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antiparkinsonian medication


A medicine used to treat Parkinson's disease. For more information see what patients on our Patient Council have to share on the topic of medication. Ataxia
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athetosis


A movement disorder sometimes confused with Parkinson's disease that manifests in low, repetitive, involuntary, writhing movements of the arms, legs, hands, and neck that are often especially sev [..]
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basal ganglia


A region deep within the brain consisting of large clusters of neurons responsible for voluntary movements such as walking and movement coordination. Many of the symptoms of Parkinson's disease a [..]
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biomarkers


Specific, measurable physical traits used to determine or indicate the effects or progress of a disease or condition. For example, high blood pressure is a biomarker of potential cardiovascular diseas [..]
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bradykinesia


One of the cardinal clinical features of Parkinson's disease, the slowing down and loss of spontaneous and voluntary movement. From the Greek brady, slow, and kinesia, movement. [..]
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