A substance that the immune system perceives as being foreign or dangerous. The body combats an antigen with the production of an antibody.

See: PSA.

Any substance that causes the body to make an immune response against that substance. Antigens include toxins, chemicals, bacteria, viruses, or other substances that come from outside the body. Body t [..]

(an-teh-jen) [Gk. anti, against + genos, origin, descent] A foreign macromolecule that does not belong to the host organism and that elicits an immune response.

Substance or a structural part (epitope) of a substance which causes the immune system to produce specific antibody or specific cells and which combines with specific binding sites (epitopes) on the a [..]

Foreign substance that, when introdued into the blood or tissues, causes the formation of antibodies.  Antigens may be toxins or native proteins.

Any substance or item that the body of an animal would regard as strange or unwanted; a foreign disease or virus in the body (toxin, etc.)

1. Substance that causes the production of an antibody that binds to the antigen in order to damage, neutralize or kill it. 2. The presence of certain antigens on blood cells is the basis for blood typing for transfusions. Antigens that are present on tissue allow for donor-recipient matching in transplant medicine.

any substance, almost always a protein, not normally present in the body which when introduced to the body stimulates a specific immune response and the production of antibodies.

"substance that causes production of an antibody," 1908, from German Antigen, from French antigène (1899), from anti- (see anti-) + Greek -gen (see -gen).

A substance that causes the body to make an immune response. This immune response often involves making antibodies.

A substance that, when introduced into the body, stimulates production of an antibody.

A substance that stimulates an immune response when introduced into the body.

Substance that is recognized by the immune system and elicits an immune response. © 2005 by W. H. Freeman and Company. All rights reserved. Pierce, B. Genetics: A conceptual approach. 2nd Edit [..]

(an´tu1-jen) A molecule that can induce the production of antibodies and react in a specific manner with antibodies. antigenic determinant site

A foreign (nonself) substance (such as a protein, nucleoprotein, polysaccharide, and some glycolipids) to which lymphocytes respond; also known as an immunogen because it induces the immune response. antigen challenge

n. any substance that is recognized by the immune system as being foreign and therefore dangerous. The body then produces antibodies that render it harmless. The antigen may be a virus, a bacterium, a [..]

foreign substance (pop)

A substance that, when introduced into the body, stimulates the production of an antibody.

A compound that induces the formation of a specific antibody.

A chemical that is capable of inducing antibody production when introduced into a person. Antigens include viruses, bacteria, and parasites, and also agents of allergy such as pollen and certain chemi [..]

A foreign substance that triggers antibody formation and is bound by the corresponding antibody.

A chemical that triggers an immune response by binding to a specific antibody

A substance that stimulates the generation of antibodies as part of an immune response.

Any of the various substances that, when recognized as non-self by the adaptive immune system, triggers an immune response, stimulating the production of an antibody

(French : antigène) A substance which has the power of inducing, in man or in an animal, the formation of antibodies.

Substances that are capable of causing the production of antibodies. Antigens may or may not lead to an allergic reaction.

a substance, usually a protein molecule or cellular component, that is foreign to the body and stimulates an immune reaction.

An antigen is a ligand that contains a region or epitope which is specifically recognized by an antibody binding site.

[noun] A substance that stimulates the production of an antibody by the immune system. Antigens include toxins, bacteria, foreign blood cells, and cells of transplanted organs. Appears in modules:

A foreign substance that binds to an antibody and starts an immune response in the body.

any foreign substance that causes an immune response. aorta

Foreign substance (almost always a protein) that, when introduced into the body, stimulates an immune response.

(n) any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

In immunology, an antigen is a substance that evokes the production of one or more antibodies. Each antibody binds to a specific antigen by way of an interaction similar to the fit between a lock and [..]

A chemical substance that stimulates an immune system response. This reaction often involves production of antibodies. For example, the immune system's response to antigens that are part of bacte [..]

Any substance that the body sees as harmful or foreign, causing the immune system to form antibodies in defense.

A substance in the blood that helps trigger the immune system to develop antibodies. See blood group.

Any substance that causes the body to produce natural antibodies.

A substance on the surface of red Blood cells that elicits an immune response when transfused into a patient who lacks that antigen.

A cell marker produced by all cell types.  Antigens help the body’s immune system identify cells.  The immune system uses antibodies to bind to the antigens in order to mark the cells for removal.

An invading substance that may be the target of antibodies.

[anti-, against + gen, producer] (n) a substance that, when introduced into the body, induces an immune response consisting of the production of a circulating antibody

a substance, such as a virus or bacterium, which the body’s immune system recognises as 'foreign'. The immune system responds by producing antibodies against the antigen.

Any substance that causes the body to produce natural antibodies.

Definition: (AN-tee-jen) Any substance that stimulates the immune system. Antigens are often foreign substances such as bacteria or viruses that invade the body. The role of the prostate-specific anti [..]

An antigen is any substance that the body regards as foreign or dangerous and against which it produces an antibody.

Any material (usually foreign) that elicits production of and is specifically bound by an antibody.

Antigens are molecules that evoke an immunological response from the body. Most antigens are proteins but they can be almost any molecule including carbohydrates, DNA and RNA. Because many proteins ar [..]

A substance that the organism identifies as foreign, hence triggering the release of antibodies as a defence response. Antigène

The descriptor applied to any substance that produces a specific immune response and is regognised as foreign by the immune system when it enters the tissue of an animal or human.

A substance, usually a protein, which the body perceives as foreign.

a substance that is capable of eliciting an immune response.

Substances that are recognized by the Immune System and induce an immune reaction.

A 13.2-kDa member of the S-100 Family of Calcium-Binding Proteins that can form homo- or heterocomplexes with Calgranulin A and a variety of other Proteins. The Calgranulin A/B heterodimer is known as [..]

Carbohydrate Antigen most commonly seen in Tumors of the Ovary and occasionally seen in Breast, Kidney, and Gastrointestinal Tract Tumors and normal Tissue. CA 125 is clearly Tumor-associated but not [..]

A major adhesion-associated heterodimer molecule expressed by Monocytes; Granulocytes; NK Cells; and some Lymphocytes. The alpha subunit is the CD11c Antigen, a Surface Antigen expressed on some Myelo [..]

Dimeric Cell surface receptor involved in angiogenesis (Neovascularization, Physiological) and axonal guidance. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 Semaphorins, and seve [..]

This intrgrin is a key component of Hemidesmosomes and is required for their formation and Maintenance in Epithelial Cells. Integrin alpha6beta4 is also found on Thymocytes, Fibroblasts, and Schwann C [..]

Those Hepatitis B Antigens found on the surface of the Dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the Surface Antigen are known. These were formerly ca [..]

A full-length splicing isoform of CD45 Antigen.

A Family of Cell-Surface Proteins found on Antigen-Presenting Cells. B7 Antigens are Ligands for specific Cell surface receptor subtypes found on T-Cells. They play an immunomodulatory Role by stimula [..]

A costimulatory ligand expressed by Antigen-Presenting Cells that binds to CTLA-4 Antigen with high specificity and to CD28 Antigen with low specificity. The interaction of CD80 with CD28 Antigen prov [..]

Carbohydrate Antigens expressed by malignant Tissue. They are useful as Tumor markers and are measured in the Serum by means of a Radioimmunoassay employing Monoclonal Antibodies.

Glycoproteins expressed on cortical Thymocytes and on some Dendritic Cells and B-Cells. Their structure is similar to that of MHC Class I and their function has been postulated as similar also. CD1 An [..]

Also known as CD104 Antigen, this protein is distinguished from other beta Integrins by its relatively long cytoplasmic domain (approximately 1000 Amino Acids vs. approximately 50). Five alternatively [..]

Cytokine-induced Cell Adhesion molecule present on activated Endothelial Cells, Tissue Macrophages, dendritic Cells, Bone Marrow Fibroblasts, Myoblasts, and Myotubes. It is important for the recruitme [..]

A receptor for Macrophage Colony-Stimulating Factor encoded by the c-fms Proto-Oncogene (Genes, fms). It contains an intrinsic Protein-Tyrosine Kinase activity. When activated the receptor undergoes a [..]

Receptors that bind and internalize the Granulocyte-Macrophage stimulating factor. Their MW is believed to be 84 kD. The most mature myelomonocytic Cells, specifically Human Neutrophils, Macrophages, [..]

A receptor subunit that combines with Cytokine Receptor gp130 to form the dual specificity receptor for Leukemia Inhibitory Factor and Oncostatin M. The subunit is also a component of the Ciliary Neur [..]

An alpha-integrin subunit found on Lymphocytes, Granulocytes, Macrophages and Monocytes. It combines with the Integrin beta2 subunit (CD18 Antigen) to form Lymphocyte Function-Associated Antigen-1.

An integrin alpha subunit of approximately 150-kDa Molecular Weight. It is expressed at high levels on Monocytes and combines with CD18 Antigen to form the Cell surface receptor Integrin alphaXbeta2. [..]

A Tumor Necrosis Factor Receptor subtype that has specificity for Tumor Necrosis Factor alpha and Lymphotoxin alpha. It is constitutively expressed in most Tissues and is a key mediator of Tumor Necro [..]

A Tumor Necrosis Factor Receptor subtype that is expressed primarily in Immune System Cells. It has specificity for Membrane-bound form of Tumor Necrosis Factors and mediates intracellular-signaling t [..]

A low affinity Interleukin-3 Receptor subunit that combines with the Cytokine Receptor Common beta Subunit to form a high affinity receptor for Interleukin-3.

A receptor subunit that is a component of the Type I Interleukin-4 Receptor and the Type II Interleukin-4 Receptor. It signals through interaction of its cytoplasmic domain with Janus Kinases such as [..]

A low affinity Interleukin-5 Receptor subunit that combines with the Cytokine Receptor Common beta Subunit to form a high affinity receptor for Interleukin-5. Several Isoforms of the Interleukin-5 Rec [..]

A low affinity Interleukin-7 receptor subunit that combines with the Interleukin Receptor Common gamma Subunit to form a high affinity receptor for Interleukin-7.

A Cell surface receptor that specifically mediates the biological effects of Interleukin-9. The functional IL9 receptor signals through interaction of its Cytoplasm domain with Janus Kinases and requi [..]

Zinc-binding Metalloproteases that are members of the type II integral Membrane Metalloproteases. They are expressed by Granulocytes; Monocytes; and their precursors as well as by various non-hematopo [..]

A receptor subunit that is a shared component of the Interleukin-3 Receptor; the Interleukin-5 Receptor; and the GM-CSF Receptor. High affinity receptor complexes are formed with each of these recepto [..]

An Interleukin Receptor subunit that was originally discovered as a component of the Interleukin 2 Receptor. It was subsequently found to be a component of several other receptors including the Interl [..]

A Tumor Necrosis Family receptor with specificity for OX40 Ligand. It is found on the surface of activated T-Lymphocytes where it plays a Role in enhancing cytokine production and proliferation of CD4 [..]

A receptor Tyrosine Kinase that is involved in Hematopoiesis. It is closely related to fms Proto-Oncogene Protein and is commonly mutated in Acute Myeloid Leukemia.

A member of the Tumor Necrosis Factor Receptor superfamily that is specific for 4-1BB Ligand. It is found in a variety of immune Cell types including activated T-Lymphocytes; Natural Killer Cells; and [..]

A Syndecan that interacts with Extracellular Matrix Proteins and plays a Role Cell Proliferation and Cell MIGRATION.

A PDGF Receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a Protein-Tyrosine Kinase activity that is involved in Signal Transduction.

A PDGF Receptor that binds specifically to the PDGF-B chain. It contains a Protein-Tyrosine Kinase activity that is involved in Signal Transduction.

A Cell Adhesion molecule of the Immunoglobulin superfamily that is expressed in Endothelial Cells and is involved in Intercellular Junctions.

A widely distributed Cell surface transmembrane Glycoprotein that stimulates the synthesis of Matrix Metalloproteinases. It is found at high levels on the surface of malignant Neoplasms and may play a [..]

A Membrane-bound Tumor Necrosis Family member found primarily on activated T-Lymphocytes that binds specifically to CD30 Antigen. It may play a Role in Inflammation and immune Regulation.

A Membrane Glycoprotein and differentiation Antigen expressed on the surface of T-Cells that binds to CD40 Antigens on B-Lymphocytes and induces their proliferation. Mutation of the Gene for CD40 liga [..]

A KIR Receptor that has specificity for HLA-C Antigens. It is an inhibitory receptor that contains D1 and D2 extracellular Immunoglobulin-like domains and a long cytoplasmic tail. It is similar in str [..]

A KIR Receptor that has specificity for HLA-C Antigen. It is an inhibitory receptor that contains D1 and D2 extracellular Immunoglobulin-like domains and a long cytoplasmic tail. It is similar in stru [..]

A KIR Receptor that has specificity for HLA-C Antigens. It is an inhibitory receptor that contains D1 and D2 extracellular Immunoglobulin-like domains and a long cytoplasmic tail. It is similar in str [..]

A KIR Receptor that has specificity for HLA-G Antigen. It contains D0 and D2 extracellular Immunoglobulin-like domains and a long cytoplasmic tail.

A KIR Receptor that has specificity for HLA-A3 Antigen. It is an inhibitory receptor that contains D0, D1, and D2 extracellular Immunoglobulin-like domains and a long cytoplasmic tail.

A Sialomucin protein that functions as a Cell Adhesion molecule. It is a negative regulator of certain types of Hematopoietic Stem Cells.

A transmembrane protein belonging to the Tumor Necrosis Factor superfamily that was originally discovered on Cells of the lymphoid-myeloid lineage, including activated T-Lymphocytes and Natural Killer [..]

Differentiation Antigens expressed on B-Lymphocytes and B-Cell precursors. They are involved in Regulation of B-Cell Proliferation.

CCR Receptors with specificity for a broad variety of CC Chemokines. They are expressed at high levels in Monocytes; Tissue Macrophages; Neutrophils; and Eosinophils.

CCR Receptors with specificity for Chemokine CCL17 and Chemokine CCL22. They are expressed at high levels in T-Lymphocytes; Mast Cells; Dendritic Cells; and NK Cells.

CCR Receptors with specificity for Chemokine CCL19 and Chemokine CCL21. They are expressed at high levels in T-Lymphocytes; B-Lymphocytes; and Dendritic Cells.

A major histocompatibily complex class I-like protein that plays a unique Role in the presentation of lipid Antigens to Natural Killer T-Cells.

Glycoprotein members of the Immunoglobulin superfamily which participate in T-Cell Adhesion and activation. They are expressed on most peripheral T-Lymphocytes, Natural Killer Cells, and Thymocytes, a [..]

Unglycosylated phosphoproteins expressed only on B-Cells. They are regulators of transmembrane Ca2+ conductance and thought to play a Role in B-Cell activation and proliferation.

Molecular sites on or in B-Lymphocytes, Follicular Dendritic Cells, lymphoid Cells, and Epithelial Cells that recognize and combine with Complement C3d. Human Complement Receptor 2 (CR2) serves as a r [..]

An Interleukin Receptor subunit with specificity for Interleukin-13. It dimerizes with the Interleukin-4 Receptor alpha Subunit to form the Type II Interleukin-4 Receptor which has specificity for bot [..]

An Interleukin-13 Receptor subunit that is closely-related to the Interleukin-13 Receptor alpha1 Subunit. The receptor is found as a monomeric protein and has been considered to be a decoy receptor fo [..]

A lectin and Cell Adhesion molecule found in B-Lymphocytes. It interacts with Sialic Acids and mediates signaling from B-Cell Antigen Receptors.

Specific molecular sites on the surface of B- and T-Lymphocytes which combine with IgEs. Two subclasses exist: low affinity receptors (Fc epsilon RII) and high affinity receptors (Fc epsilon RI).

A Cell Adhesion protein that was originally identified as a Heat stable Antigen in Mice. It is involved in Metastasis and is highly expressed in many Neoplasms.

A low affinity Interleukin-2 receptor subunit that combines with the Interleukin-2 Receptor beta Subunit and the Interleukin Receptor Common gamma-Chain to form a high affinity receptor for Interleuki [..]

A Tumor Necrosis Factor superfamily member that plays a Role in the Regulation of B-Lymphocyte Survival. It occurs as a Membrane-bound protein that is cleaved to release an biologically active soluble [..]

A Serine Protease that Catalyses the release of an N-terminal dipeptide. Several biologically-active Peptides have been identified as dipeptidyl peptidase 4 substrates including Incretins; Neuropeptid [..]

A Tumor Necrosis Factor Receptor superfamily member found expressed on peripheral B-Lymphocytes. It has specificity for B-Cell Maturation Antigen and Tumor Necrosis Factor Ligand Superfamily Member 13 [..]

A member of the Tumor Necrosis Factor Receptor superfamily that specifically binds B-Cell Activating Factor. It is found on B-Lymphocytes and plays a Role in maturation and Survival of B-Cells. Signal [..]

A costimulatory B7 Antigen that has specificity for the T-Cell Receptor Programmed Cell Death 1 Receptor. It is closely-related to CD274 Antigen; however, its expression is restricted to Dendritic Cel [..]

An inhibitory B7 Antigen that has specificity for the T-Cell Receptor Programmed Cell Death 1 Protein. CD274 Antigen provides negative signals that control and inhibit T-Cell responses and is found at [..]

A B7 Antigen that binds specifically to Inducible T-Cell Co-Stimulator Protein on T-Cells. It provides a costimulatory signal for T-Cell Proliferation and cytokine Secretion.

A costimulatory receptor that is specific for Inducible T-Cell Co-Stimulator Ligand. The receptor is associated with a diverse array of immunologically-related effects including the increased synthesi [..]

An inhibitory T-Lymphocyte receptor that has specificity for CD274 Antigen and Programmed Cell Death 1 Ligand 2 Protein. Signaling by the receptor limits T Cell Proliferation and Interferon GAMMA synt [..]

Costimulatory T-Lymphocyte receptors that have specificity for CD80 Antigen and CD86 Antigen. Activation of this receptor results in increased T-Cell Proliferation, cytokine production and promotion o [..]

Cell Adhesion Molecules present on virtually all Monocytes, Platelets, and Granulocytes. CD31 is highly expressed on Endothelial Cells and concentrated at the junctions between them.

A Cell Adhesion protein that is found within Tight Junctions of Endothelial Cells and on the Cell Membrane surface of circulating Platelets.

A Junctional Adhesion Molecule subtype that is localized to high endothelial Venules, Heart Endothelium, Trophoblasts of the PLANCENTA, and in the Endothelium of Arterioles.

A 67-kDa Sialic Acid binding lectin that is specific for Myeloid Cells and Monocyte-Macrophage Precursor Cells. This protein is the smallest Siglec subtype and contains a single Immunoglobulin C2-set [..]

A 46-kD stimulatory receptor found on resting and activated Natural Killer Cells. It has specificity for Viral Hemagglutinins that are expressed on infected Cells.

A 44-kD stimulatory receptor found on activated Natural Killer Cells. It has specificity for Viral Hemagglutinins that are expressed on infected Cells.

A 30 kDa stimulatory receptor found on resting and activated Natural Killer Cells.

Glycoproteins found on immature hematopoietic Cells and Endothelial Cells. They are the only molecules to date whose expression within the Blood system is restricted to a small number of Progenitor Ce [..]

Molecular sites on or in some B-Lymphocytes and Macrophages that recognize and combine with Complement C3b. The primary structure of these receptors reveal that they contain transmembrane and cytoplas [..]

55-kDa Antigens found on Helper-Inducer T-Lymphocytes and on a variety of other immune Cell types. CD4 Antigens are members of the Immunoglobulin supergene Family and are implicated as associative rec [..]

A Sialic Acid-rich protein and an integral Cell Membrane Mucin. It plays an important Role in activation of T-Lymphocytes.

Acidic sulfated integral Membrane Glycoproteins expressed in several alternatively spliced and variable glycosylated Forms on a wide variety of Cell types including mature T-Cells, B-Cells, medullary [..]

A ubiquitously expressed Complement Receptor that binds Complement C3b and Complement C4b and serves as a cofactor for their inactivation. CD46 also interacts with a wide variety of pathogens and medi [..]

An integrin alpha subunit that binds Collagen and Laminin though its I domain. It combines with Integrin beta1 to form the heterodimer Integrin alpha1beta1.

An integrin alpha subunit that primarily combines with Integrin beta1 to form the Integrin alpha2beta1 heterodimer. It contains a domain which has homology to Collagen-binding domains found in von Wil [..]

An integrin alpha subunit that occurs as alternatively spliced Isoforms. The Isoforms are differentially expressed in specific Cell types and at specific developmental stages. Integrin alpha3 combines [..]

An integrin alpha subunit that is unique in that it does not contain an I domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close [..]

This integrin alpha subunit combines with Integrin beta1 to form a receptor (Integrin alpha5beta1) that binds Fibronectin and Laminin. It undergoes posttranslational cleavage into a heavy and a Light [..]

An integrin alpha subunit that primarily associates with Integrin beta1 or Integrin beta4 to form Laminin-binding heterodimers. Integrin alpha6 has two alternatively spliced Isoforms: integrin alpha6A [..]

Glycoproteins expressed on all mature T-Cells, Thymocytes, and a subset of mature B-Cells. Antibodies specific for CD5 can enhance T-Cell Receptor-mediated T-Cell activation. The B-Cell-specific molec [..]

An alpha integrin with a Molecular Weight of 160-kDa that is found in a variety of Cell types. It undergoes posttranslational cleavage into a heavy and a Light chain that are connected by disulfide bo [..]

Tetraspanin Proteins found at high levels in Cells of the lymphoid-myeloid lineage. CD53 Antigens may be involved regulating the differentiation of T-Lymphocytes and the activation of B-Lymphocytes.

A Cell-surface ligand involved in Leukocyte adhesion and Inflammation. Its production is induced by gamma-Interferon and it is required for Neutrophil migration into inflamed Tissue.

Glycoproteins with a wide distribution on hematopoietic and non-hematopoietic Cells and strongly expressed on Macrophages. CD58 mediates Cell Adhesion by binding to CD2; (Antigens, CD2); and this enha [..]

An integrin beta subunit of approximately 85-kDa in size which has been found in Integrin alphaIIb-containing and Integrin alphaV-containing heterodimers. Integrin beta3 occurs as three alternatively [..]

Cell Adhesion molecule and CD Antigen that mediates Neutrophil, Monocyte, and Memory T-Cell Adhesion to cytokine-activated Endothelial Cells. E-selectin recognizes sialylated carbohydrate groups relat [..]

Cell Adhesion molecule and CD Antigen that mediates the adhesion of Neutrophils and Monocytes to activated Platelets and Endothelial Cells.

Ubiquitously-expressed tetraspanin Proteins that are found in late Endosomes and Lysosomes and have been implicated in intracellular transport of Proteins.

A Glycoprotein that is secreted into the luminal surface of the epithelia in the Gastrointestinal Tract. It is found in the Feces and pancreaticobiliary Secretions and is used to monitor the response [..]

Differentiation Antigens expressed on pluripotential hematopoietic Cells, most Human Thymocytes, and a major subset of peripheral Blood T-Lymphocytes. They have been implicated in integrin-mediated ce [..]

A transmembrane protein belonging to the Tumor Necrosis Factor superfamily that specifically binds to CD27 Antigen. It is found on activated T-Lymphocytes; B-Lymphocytes; and Dendritic Cells where it [..]

A Glycoprotein enzyme present in various organs and in many Cells. The enzyme catalyzes the Hydrolysis of a 5'-ribonucleotide to a ribonucleoside and orthophosphate in the presence of Water. It i [..]

A component of the B-Cell Antigen Receptor that is involved in B-Cell Antigen Receptor heavy chain transport to the Plasma Membrane. It is expressed almost exclusively in B-Lymphocytes and serves as a [..]

Differentiation Antigens found on Thymocytes and on cytotoxic and suppressor T-Lymphocytes. CD8 Antigens are members of the Immunoglobulin supergene Family and are associative recognition Elements in [..]

A widely expressed transmembrane Glycoprotein that functions as a Metastasis suppressor protein. It is underexpressed in a variety of Human Neoplasms.

A costimulatory ligand expressed by Antigen-Presenting Cells that binds to CD28 Antigen with high specificity and to CTLA-4 Antigen with low specificity. The interaction of CD86 with CD28 Antigen prov [..]

An extracellular receptor specific for Urokinase-Type Plasminogen Activator. It is attached to the Cell Membrane via a Glycosylphosphatidylinositol LINKAGE and plays a Role in the co-localization of U [..]

A G-Protein-coupled receptor that signals an increase in intracellular Calcium in response to the potent ANAPHYLATOXIN peptide Complement C5a.

A subtype of tetraspanin Proteins that play a Role in Cell Adhesion, Cell motility, and Tumor Metastasis. CD9 Antigens take part in the process of Platelet Activation and aggregation, the formation of [..]

A LDL-receptor related protein involved in clearance of Chylomicron Remnants and of activated alpha-Macroglobulins from Plasma.

A heterodimeric protein that is a Cell Surface Antigen associated with Lymphocyte Activation. The initial characterization of this protein revealed one identifiable heavy chain (Antigens, CD98 Heavy C [..]

A subunit of the Interleukin-10 Receptor. It plays a Role in receptor signaling by associating with TYK2 Kinase.

A subunit of the Interleukin-18 Receptor that is responsible of extracellular binding of IL-18.

A subunit of the Interleukin-18 Receptor that plays a Role in receptor signaling by Association of its cytoplasmic domain with Signal Transducing Adaptor Proteins such as Myeloid Differentiation Facto [..]

Integrin beta-1 chains which are expressed as heterodimers that are noncovalently associated with specific alpha-chains of the CD49 Family (CD49a-f). CD29 is expressed on resting and activated Leukocy [..]

A member of the Tumor Necrosis Factor Receptor superfamily with specificity for CD40 Ligand. It is found on mature B-Lymphocytes and some Epithelial Cells, lymphoid Dendritic Cells. Evidence suggests [..]

An inhibitory T Cell Receptor that is closely related to CD28 Antigen. It has specificity for CD80 Antigen and CD86 Antigen and acts as a negative regulator of peripheral T Cell function. CTLA-4 Antig [..]

A 10.8-kDa member of the S-100 Family of Calcium-Binding Proteins that can form homo- or heterocomplexes with Calgranulin B and a variety of other Proteins. The Calgranulin A/B heterodimer is known as [..]

Antigen detected when Eosinophil granules are released.

Carbohydrate Antigen elevated in Patients with Tumors of the Breast, Ovary, Lung, and Prostate as well as other disorders. The Mucin is expressed normally by most glandular epithelia but shows particu [..]

A glycolipid, cross-species Antigen that induces production of antisheep hemolysin. It is present on the Tissue Cells of many species but absent in Humans. It is found in many infectious agents.

Sialylated Lewis Blood group carbohydrate Antigen found in many Adenocarcinomas of the Digestive Tract, especially pancreatic Tumors.

Antigens produced by various strains of Hepatitis D Virus.

A group of Antigens that includes both the major and Minor Histocompatibility Antigens. The former are genetically determined by the Major Histocompatibility Complex. They determine Tissue type for Tr [..]

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*14 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*15 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*38 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*44 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*52 Allele Family.

A specific HLA-A Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-A*01 Allele Family.

A specific HLA-A Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-A*02 Allele Family.

A specific HLA-A Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-A*24 Allele Family.

A specific HLA-A Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-A*03 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*13 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*18 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*27 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*35 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*37 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*39 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*40 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*51 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*07 Allele Family.

A specific HLA-B Surface Antigen subtype. Members of this subtype contain alpha chains that are encoded by the HLA-B*08 Allele Family.

An HLA-DR Antigen associated with HLA-DRB1 Chains that are encoded by DRB1*01 Alleles.

A broad specificity HLA-DR Antigen that is associated with HLA-DRB1 Chains encoded by DRB1*01:15 and DRB1*01:16 Alleles.

An HLA-DR Antigen which is associated with HLA-DRB1 Chains encoded by DRB1*03 Alleles.

An HLA-DR Antigen which is associated with HLA-DRB1 Chains encoded by DRB1*04 Alleles.

A broad-specificity HLA-DR Antigen that is associated with HLA-DRB1 Chains encoded by DRB1*11 and DRB1*12 Alleles.

A broad-specificity HLA-DR Antigen that is associated with HLA-DRB1 Chains encoded by DRB1*13 and DRB1*14 Alleles.

A HLA-DR Antigen that is associated with HLA-DRB1 Chains encoded by DRB1*07 Alleles.

A subtype of HLA-DRB beta chains that includes over one hundred Allele variants. The HLA-DRB1 subtype is associated with several of the HLA-DR Serological Subtypes.

A subtype of HLA-DRB beta chains that includes over 50 allelic variants. The HLA-DRB3 beta-chain subtype is associated with HLA-DR52 serological subtype.

A subtype of HLA-DRB beta chains that is associated with the HLA-DR53 serological subtype.

A subtype of HLA-DRB beta chains that is associated with the HLA-DR51 serological subtype.

Class I Human Histocompatibility (HLA) Surface Antigens encoded by Alleles on locus B of the HLA complex. The HLA-G Antigens are considered non-classical Class I Antigens due to their distinct Tissue [..]

HuD paraneoplastic Encephalomyelitis Antigen is an RNA-Binding Protein. It binds AU-rich sequences in the 3' Untranslated Regions of mRNAs for Proto-Oncogene Proteins c-fos; Cyclin-Dependent Kina [..]

Platelet Membrane Glycoprotein IIb is an integrin alpha subunit that heterodimerizes with Integrin beta3 to form Platelet Glycoprotein GPIIb-IIIa Complex. It is synthesized as a single polypeptide cha [..]

A sex-specific Cell Surface Antigen produced by the sex-determining Gene of the Y Chromosome in Mammals. It causes synGeneic Grafts from males to females to be rejected and interacts with somatic Elem [..]

Large, transmembrane, non-covalently linked Glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II Antigens in Huma [..]

A ubiquitously expressed Membrane Glycoprotein. It interacts with a variety of Integrins and mediates responses to Extracellular Matrix Proteins.

An enzyme that activates Histidine with its specific Transfer RNA. EC 6.1.1.21.

A member of the Tumor Necrosis Factor Receptor superfamily that may play a Role in the Regulation of NF-kappa B and Apoptosis. They are found on activated T-Lymphocytes; B-Lymphocytes; Neutrophils; Eo [..]

A member of the S-100 Protein Family that is present at high levels in the Blood and Interstitial Fluid in several infectious, inflammatory, and malignant disorders, including Rheumatoid Arthritis, In [..]

A group of dominantly and independently inherited Antigens associated with the ABO Blood factors. They are Glycolipids present in Plasma and Secretions that may adhere to the Erythrocytes. The Phenoty [..]

Oligosaccharide Antigenic Determinants found principally on NK Cells and T-Cells. Their Role in the immune response is poorly understood.

High-Molecular Weight Glycoproteins uniquely expressed on the surface of Leukocytes and their hemopoietic progenitors. They contain a cytoplasmic Protein Tyrosine Phosphatase activity which plays a Ro [..]

A trisaccharide Antigen expressed on Glycolipids and many Cell-Surface Glycoproteins. In the Blood the Antigen is found on the surface of Neutrophils; Eosinophils; and Monocytes. In addition, CD15 Ant [..]

An inhibitory subclass of NK Cell Lectin-Like Receptors that interacts with Class I Major Histocompatibility Antigens and prevents the activation of NK Cells.

An adhesion-promoting Leukocyte surface Membrane heterodimer. The alpha subunit consists of the CD11b Antigen and the beta subunit the CD18 Antigen. The Antigen, which is an integrin, functions both a [..]

A multifunctional galactin initially discovered as a Macrophage Antigen that binds to Immunoglobulin E, and as 29-35-kDa lectin that binds Laminin. It is involved in a variety of biological events inc [..]

A Melanosome-specific protein that plays a Role in the expression, stability, trafficking, and processing of gp100 Melanoma Antigen, which is critical to the formation of Stage II Melanosomes. The pro [..]

A Melanosome-associated protein that plays a Role in the maturation of the Melanosome.

A Cell Cycle and Tumor Growth marker which can be readily detected using IMMUNOCYTOCHEMISTRY methods. Ki-67 is a nuclear Antigen present only in the nuclei of cycling Cells.

A CD Antigen that contains a conserved I domain which is involved in ligand binding. When combined with CD18 the two subunits form Macrophage-1 Antigen.

The 140 kDa isoform of NCAM (Neural Cell Adhesion Molecule) containing a transmembrane domain and short cytoplasmic tail. It is expressed by all Lymphocytes mediating non-MHC restricted cytotoxicity a [..]

The lipopolysaccharide-protein somatic Antigens, usually from Gram-Negative Bacteria, important in the serological Classification of enteric bacilli. The O-specific chains determine the specificity of [..]

Leukocyte Differentiation Antigens and major Platelet Membrane Glycoproteins present on Monocytes; Endothelial Cells; Platelets; and mammary Epithelial Cells. They play major Roles in Cell Adhesion; S [..]

Nuclear Antigen with a Role in DNA synthesis, DNA Repair, and Cell Cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during [..]

Cell-surface molecules that exhibit lineage-restricted patterns of expression during Embryonic Development. The Antigens are useful markers in the Identification of Embryonic Stem Cells.

Antigens on surfaces of Cells, including infectious or foreign Cells or Viruses. They are usually protein-containing groups on Cell Membranes or walls and may be isolated.

Those Proteins recognized by Antibodies from Serum of Animals bearing Tumors induced by Viruses; these Proteins are presumably coded for by the Nucleic Acids of the same Viruses that caused the neopla [..]

A bifunctional enzyme that catalyzes the synthesis and Hydrolysis of Cyclic ADP-Ribose (cADPR) from NAD+ to ADP-Ribose. It is a Cell surface molecule which is predominantly expressed on LYMPHOID Cells [..]

Complex of at least five Membrane-bound polypeptides in mature T-Lymphocytes that are non-covalently associated with one another and with the T-Cell Receptor (Receptors, Antigen, T-Cell). The CD3 comp [..]

Tetraspanin Proteins that are involved in a variety of cellular functions including Basement Membrane assembly, and in the formation of a molecular complexes on the surface of Lymphocytes.

A member of the Tumor Necrosis Factor Receptor superfamily found on most T-Lymphocytes. Activation of the receptor by CD70 Antigen results in the increased proliferation of CD4-Positive T-Lymphocytes [..]

A group of differentiation Surface Antigens, among the first to be discovered on Thymocytes and T-Lymphocytes. Originally identified in the Mouse, they are also found in other species including Humans [..]

Serological Tumor marker composed of a molecular complex of cytokeratins 8, 18, and 19. It is used in the Diagnosis and staging of Bronchogenic Carcinoma.

Cell Adhesion molecule and CD Antigen that serves as a homing receptor for Lymphocytes to Lymph Node high endothelial Venules.

Any substance that is foreign to the body and triggers an immune response. Antigens include bacteria, viruses, and allergens, such as pollen. See Related Term(s): Immune Response

Any large molecule that stimulates the production of specific antibodies or that binds specifically to an antibody.

Any substance that can stimulate an immune response.

Any material that is recognized by the immune system as dissimilar to “organism owned structures”. Antigens can be recognized and bound by an antibody. Tumor antigens can be found on the surface of cancerous cells or can be released into the surrounding tumor cell environment.

A foreign substance that stimulates the body to defend itself with an immune response.

Any substance that causes the body to produce natural antibodies.

A substance that provokes the immune system to generate antibodies against it.

 A substance that can produce a specific immune response

Any substance foreign to the body that evokes an immune response either alone or after forming a complex with a larger protein. Antigens are active components of a vaccine that stimulate the body to p [..]

any substance that stimulates the immune system to produce antibodies. Antigens are often foreign substances such as invading bacteria or viruses. (See also immunogen.)

An antigen is defined as anything that provokes an immune response, which is specific to that material. It can be a single molecule, or a more complex structure such as a bacteria or virus.

a foreign substance, such as a virus, that enters the body and induces an immune response. Similar to a lock and key, antigens specifically bind to their respective antibodies via the epitopes that ar [..]

Any of various foreign substances such as bacteria, viruses, endotoxins, exotoxins, foreign proteins, pollen, and vaccines, whose entry into an organism induces an immune response (antibody production [..]

a foreign substance (such as a virus) that enters the body causes the body’s immune system to respond.

a foreign substance (usually a protein or carbohydrate) capable of triggering an immune response in an organism.

A substance which triggers an immune response as part of the body's protection against foreign substances or organisms. Back to top

An Antigent is a substance that triggers an immune response, for example through the production of antibodies

is any substance that causes your immune system to produce antibodies against it. An antigen may be a foreign substance from the environment such as chemicals, bacteria, viruses, or pollen. An antigen may also be formed within the body, as with bacterial toxins or tissue cells

A substance that stimulates the production of antibodies. Examples include pollen grains, dust, bacteria or viruses and most proteins.

substances that can combine with an antibodies; the 'active ingredient' in vaccines

Any substance that stimulates an immune response by the body. The immune system recognizes such substances as being foreign, and produces cellular antibodies to fight them. Antigen/antibody response i [..]

    An antigen is any foreign component that triggers an immune response.  Antigens are recognized by antibodies that in turn direct the immune response.  The term “antigen” historically comes from antibody generator. Antigens themselves can be proteins or polysaccharides. They are often components of the invading microorganism such as their cell w [..]

A foreign substance that can elicit an immune response

A substance that causes the immune system to respond. Common antigens include viruses, bacteria, foreign cells, pollen, and dust.

A protein or other substance capable of triggering an immune response.

 The part of a ‘foreign’ substance that has entered the body that is recognised by the immune system, which then stimulates a defensive response in the form of an antibody; the foreign substance is usually a protein

Any substance that stimulates the production of antibodies in the body. For example, pollen grains, dust, bacteria and viruses are recognised by the body as being foreign and it responds by producing specific antibodies to the antigen.

anything (usually a protein) that elicits an immune response.  Bacteria and viruses are two examples of antigens.

A foreign substance that elicits the production of antibodies.

An antigen is a substance that can trigger an immune response, resulting in production of an antibody as part of the body's defense against infection and disease. Many antigens are foreign proteins (those not found naturally in the body). An allergen is a special type of antigen which causes an IgE antibody response.

an agent to which an antibody binds.

Any substance capable of eliciting an immune response.

Substance that reacts with an antibody. It contains an area on its surface to which antibody binds.

An antigen is a substance that can trigger an immune response, resulting in production of an antibody as part of the body's defense against infection and disease. Many antigens are foreign proteins (those not found naturally in the body). An allergen is a special type of antigen which causes an IgE antibody response.

A molecule, molecular assembly, or organism that is specifically recognized by an antibody.

A harmful invader of the immune system. A substance that can trigger an immune response, resulting in the production of antibodies as part of the body's immune system.

Any structural substance which serves as a target for the receptors of an adaptive immune response. For example, dietary proteins, environmental molecules, chemical molecules. Protein structures than can elicit an immune response.

A harmful invader of the immune system. A substance that can trigger an immune response, resulting in the production of antibodies as part of the body's immune system.

<immunology> A protein molecule that often protrudes from the surface of a cell that can induce an immune response. The epitope is the part of the molecule that is responsible for this feature, whereas the carrier molecule results in the activity as an antigen. Usually antigens are foreign to the host animal in which they produce a response. [..]

A molecule whose shape triggers the production of antibodies (immunoglobulins) that will bind to the antigen. A foreign substance capable of triggering an immune response in an organism.

A secretion (toxin or enzyme) of fungi and bacteria that is capable of producing an immune response (allergic reaction) in humans. The reaction may be in the form of an asthma attack, eye irritation, [..]

Molecule on a cell we are trying to identify or collect.

A protein or other molecule that can elicit an immune response; the antibody protein that is produced binds to the antigen.

A substance that can incite the production of specific antibodies and can combine with those antibodies.

 a marker protein on cells of the body or foreign substances, such as a virus or bacteriaartery:

A protein or carbohydrate substance that is recognized by the body as foreign that stimulates an immune response.

any substance that stimulates the immune system to produce antibodies. The hepatitis C virus is an example of an antigen.

A substance on the surface of red blood cells that elicits an immune response when transfused into a patient who lacks that antigen.

Any substance or agent capable of stimulating an immune (antibody) response.

A foreign molecule or substance, such as a transplant, that triggers an immune response. This response may be the production of antibodies.

foreign protein that stimulates an immune response in the body.

In broad usage, any substance or entity which the body recognizes as foreign and induces the production of antibodies to neutralize or destroy the antigen. Antigens include toxins, bacteria, foreign blood cells, and the cells of transplanted organs. More specifically, the antigen is the protein marker on the surface of a cell that marks it as & [..]

A substance that causes the formation of an antibody.

A foreign molecule or substance, such as a transplant, that triggers an immune response. This response may be the production of antibodies.

a substance capable of inducing a specific immune reaction, e.g., toxins, foreign proteins, and bacteria. The presence of an antigen will evoke the existence of an antibody.

The chemical that is introduced into a person that starts and completes an immune response. When you are vaccinated (measles), the measles virus is the antigen that results in the antibody that protec [..]

Typically a foreign (not naturally occurring in the body) protein that is capable of stimulating an immune response.

Short for antibody generator. An antigen is any foreign molecule which reacts with preformed antibody and the specific receptors on T- and B-cells; also used loosely to describe materials used for immunization. (Compare to Immunogen.)

Any foreign substance (such as a bacteria, virus, toxin or tumor) that, when introduced into or arising in the body, causes the immune system to produce natural antibodies. Antineoplastic agent

A substance that is recognized by the immune system as foreign to the body.

A foreign molecule or substance that stimulates the immune system to activate a series of events to eliminate the antigen. In MS, the immune system misdirects the reactivity to antigens to damage the [..]

Any substance that causes the body’s immune system to respond. This response often involves making antibodies.

Any protein or polypeptide substance (such as a toxin or enzyme) capable of stimulating an immune response

A foreign substance that provokes an immune system response when introduced to the body. Almost any large molecule can be an antigen– including elements of bacteria, viruses, protozoa, food, and various cells and tissues.

any substance that stimulates the immune system to produce antibodies. The hepatitis C virus is an example of an antigen.

a substance which, when present in animal tissue, stimulates the production of antibodies.

In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigen [..]

A protein the immune system recognizes as "foreign"; this can be a substance such as a bacteria or toxin from an infectious disease or enzyme that stimulates an immune response, especially the production of antibodies; also called allergen, immunogen.

Any substance that can stimulate the production of antibodies and combine specifically with them.

A substance that the body recognises as foreign and that can evoke an immune response. Most often, an antigen is a peptide or protein (e.g. bacterial antigen, food antigen or toxin). 1

A substance on the surface of red blood cells that elicits an immune response when transfused into a patient who lacks that antigen.